There are a few precautions that can be taken in order to protect the information on your USB drive.
Take advantage of security features- Use things like passwords and encryption to help secure your flash drive and make sure that your data is well protected. It is also very important that you back up your data in case your data is ever lost.
Keep business and personal USB drives separate- It’s on good practice to keep personal information on the same USB drive as one containing personal information and vice versa. Likewise you shouldn’t connect a USB drive containing personal information on a business computer as you shouldn’t connect a USB drive with business information to a personal computer.
Use and maintain security software, and keep all software up to date- Firewall, anti virus and anti spyware software should all be used to help make your computer safer. Any necessary patches for your software should be applied to keep your computer up to date.
Do not plug an unknown USB drive into your computer- If you find a USB drive, you should either give it to the authorities such as your organization’s IT department or any local security personnel. You should NOT try to connect the USB drive to your computer to view the contents or identify the owner because it is possible that there may be malware inside of the drive that could infect your computer.
Disable Autorun- Autorun allows removable media to be opened automatically whenever they are connected to a computer. This is a security risk because an infected drive can connect to your computer and infect it with malicious code if autorun is not disabled.